BIOL 398J Week 2, Question #1

The most important immune system tissue for good cardiovascular health is bone marrow. Red blood cells and their production is influenced by the bone marrow and the microenvironment of this immune tissue. An imbalance of the production of blood cells can lead to the development of some cardiovascular diseases like athero-sclerosis. Cardiovascular diseases are also shown to corrupt the micro environment of the bone marrow, leading to an imbalance of blood cell production (Itkin & Rafii, 2021).

Reference

Itkin, T. & Rafii, S. (2021). Cardiovascular disease disrupt the bone-marrow niche. Nature. https://www.nature.com/articles/d41586-021-03550-y

I believe that the most important immune system tissue for good cardiovascular health is bone marrow. Bone marrow is located inside some of the bones in our body (National Heart, Lung, and, Blood Institute, 2021). Bone marrow is a spongy tissue that has stem ells in it that can be converted into red blood cells. the red blood cells responsibility to carry oxygen in the body (National Heart, Lung, and, Blood Institute, 2021). Bone marrow is extremely important when it comes to our cardiovascular health because of the relation of red blood cells and the heart (National Heart, Lung, and, Blood Institute, 2021).

 

Reference

National Heart, Lung, and, Blood Institute. (2021, December 23). Researchers uncover new link between bone marrow changes and heart disease. National Heart Lung and Blood Institute. Retrieved October 22, 2022, from https://www.nhlbi.nih.gov/news/2021/researchers-uncover-new-link-between-bone-marrow-changes-and-heart-disease

I think that Bone Marrow is the most important immune system tissue relating to heart health. New cells, such as stem cells, are made within bone marrow. These new cells can help heal damaged tissue, such as the heart. Additionally, “bone marrow releases healing substances during a heart attack” (BHF, n.d).

 

Research into bone marrow. (n.d.). British Health Foundation. https://www.bhf.org.uk/informationsupport/heart-matters-magazine/research/research-beyond-the-heart/bone-marrow-research

The immune system is vitally important to cardiovascular health, as it helps to protect the body against infection and disease. The most important immune system tissues in this regard are the lymph nodes, spleen, and thymus. These organs help filter out harmful bacteria and viruses from the blood and produce white blood cells that can fight off infections. Without a healthy immune system, the cardiovascular system would be at a much greater risk of developing infections, which can lead to serious health complications.

I believe the most important system tissues in this context is Macrophages. This is the first immune cell to appear in the organism’s development (Frodermann & Nahrendorf, n.d.). They play a key role in immunity and also help regulate organ development and function. These cells are present in all tissues and can clear cellular debris and pathogens (Frodermann & Nahrendorf, n.d.).

References

Frodermann, V., & Nahrendorf, M. (n.d.). NCBI – WWW Error Blocked Diagnostic. NCBI. Retrieved November 1, 2022, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442921/