Assignment: NUR 550 Translational Research
Assignment: NUR 550 Translational Research
Translational Research Graphic Organizer
Use the “Translational Research Graphic Organizer Template” to compare three types of translational research with traditional (qualitative or quantitative) research. Make sure to include methodology, goals, and data collection in your organizer.
You are required to cite three to five sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.
While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.
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What is Translational in health?
THE TRANSLATION OF THE ACHIEVEMENTS FROM BASIC SCIENCE into everyday clinical practice remains an important issue in contemporary health, and is addressed through the new subject of translational research, which aims to bridge the gap between basic research and its application in health. At first, it connected bench (basic) to bed research (clinical applications), which is also known as benchside-to-bedside research2. The definition of translational research has evolved over time, ceasing to be a field linked to clinical research, with perspectives that were mainly focused on the development of new health technologies.
There is an emerging consensus on four perspectives that comprise different stages of translational
research in their broad scope based on their different purposes. The first phase involves processes that bring the ideas and the discoveries of basic research at an early stage to their application in human beings. The second phase involves the establishment of efficacy in humans and clinical guidelines for the incorporation of the clinical knowledge into practice in health systems and services. The third phase focuses mainly on implementation research and the dissemination of the application of knowledge. The fourth phase focuses on results on patients and population effectiveness, as well as equity-related issues, in order to verify whether the expected effects of technologies introduced into the health system were different across population groups.
Currently, the European Society for Translational Medicine defines a broader scope for translational research as: an interdisciplinary branch of biomedical research supported by three pillars: bench, bed, and community research, whose goal is to combine subjects, resources, knowledge, and techniques, in order to promote advances in prevention, diagnosis, and therapies, aiming to significantly improve the global health system3.
The extension of the concept to health systems seems so obvious that one wonders why translational research has only recently caught the attention of health policy managers4. The field of translational research encompasses laboratory studies, clinical demands, public health and health management, policies, and economics. It is crucial in the evolution of contemporary biomedical science, and its interventions follow political-economic, ethical-social, and educational-scientific approaches. Translational research may progress by reorganizing academic teams translationally. New translation-oriented academic positions are urgently needed1. One of the reasons for the distance between basic research and its applications may lie in the increasing compartmentalization of science. Basic research, which seeks to discover the underlying principles of the natural world, is fundamentally different from applied research, which seeks to find ways to influence or control the world. Basic and applied research scientists not only differ in their training and in the tools, they bring to solve research problems, but also in the way they plan the health research process.
Aspects related to policy implementation and the development of other technology modalities, other than drugs and diagnostic testing, have gradually attracted the attention and interest of the academic community and decision-makers around the world. Increasingly, translational research also means translating knowledge into political and organizational praxis.
In order to move forward in this direction, translational research has broadened its scope and built connections to align itself with the translation of knowledge. It is defined as a systematic and transparent process of synthesis, dissemination, exchange, and ethical application of knowledge to improve results and strengthen public policies and health systems, as well as population health, encompassing all the phases in between production and effective application of scientific knowledge, in its various modalities and epistemological and methodological perspectives, in order to support more beneficial results for society.
Topic 2 DQ 2
Translational research is a branch in research that can be adopted to address ecological and global issues, social determinants of health, principles of genomics and genetics. This type of research mainly targets at converting study results into those having direct impact on the population. The basic premise of this study is that the interventions investigated in studies can be directly implemented to produce similar outcomes in addressing population health issues (Boswell & Cannon, 2022). Translational research can be applied to global issues such as global warming and health problems such as HIV/AIDS. Accordingly, the interventions that have been investigated in studies can be applied into clinical practice to address these problems. For example, research interventions such as hand washing and social distancing were directly translated into practice during Covid19 pandemic, hence, the influence of translational research.
Social determinants of health are non-medical factors that have a significant influence on a population’s health outcomes. The comprise factors such as income, education, food insecurity, working conditions, structural conflict, and access to and affordability of healthcare services (WHO, 2023). Genetics also play a role in contributing to health problems such as cancer among populations. Translational research can be applied to address these issues. For example, genetic testing can be adopted to identify and reduce the risk of specific genetic conditions in a population (Horwitz et al., 2020). Besides, nurses can implement research recommendations such as community empowerment to address the social determinants of health. therefore, researchers and healthcare providers should explore how to address issues contributing to global disease burden through translational research.
NURS 6512 Discussion Assessing Musculoskeletal Pain References
Boswell, C., & Cannon, S. (2022). Introduction to Nursing Research: Incorporating Evidence-Based Practice. Jones & Bartlett Learning.
Horwitz, L. I., Chang, C., Arcilla, H. N., & Knickman, J. R. (2020). Quantifying Health Systems’ Investment In Social Determinants Of Health, By Sector, 2017–19. Health Affairs, 39(2), 192–198. https://doi.org/10.1377/hlthaff.2019.01246
WHO. (2023). Social determinants of health. https://www.who.int/health-topics/social-determinants-of-health
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