Assignment: NUR 550 Translational Research

Assignment: NUR 550 Translational Research

Assignment: NUR 550 Translational Research

Translational Research Graphic Organizer Template

The population identified for the research involves African Americans suffering from Type 2 diabetes. African Americans are considered to have a higher risk of type 2 diabetes compared to other races. In most cases, obesity, genetic traits, as well as insulin resistance contributes to the risk of type 2 diabetes. Black Americans have the highest rates of diabetic complications as a result of the racial disparities in the healthcare system and poor glycaemic control. Afro-Americans suffering from diabetes often possess atypical presentation that simulates type 1 diabetes, however, there succeeding clinical course is a typical type 2 diabetes. Socially, the assistance from nurses, structured disease management protocols, diabetic educators, as well as the interventions of other medical professionals are some of the effective measures when it comes to the management of type 2 diabetic among the African Americans in the United States (Carpenter, DiChiacchio & Barker, 2019). Type 2 diabetes is the most common type of diabetes and it begins after forty years. The body is unable to make enough or properly use insulin which results in increased blood sugar levels. Research indicates that black adults are at higher risk of developing type 2 diabetes compared to white adults.

Synthesis of Nursing Science, Determinants of Health, and

Epidemiologic and Genetic Data

The application of nursing science is essential in the management of type 2 diabetes among African Americans. With the application of evidenced-based practices as well as the community interventions, African Americans who have low income can access the medical system and nursing care that can enable them control physiological factors that can lead to type 2 diabetes. For instance, nursing interventions that are geared towards reducing obesity are some of the essential factors when it comes to the management or control of obesity among African Americans. Changing the lifestyle, nutritional practices, and creation of a healthy environment are some of the health determinants that can be used to manage type 2 diabetes or factors that may lead to it among African Americans (Hu et al., 2016). The epidemiological approaches and genomic studies among African Americans are some of the approaches that can be used to identify the best intervention approaches in the management of type 2 diabetes or the conditions associated with it such as obesity.

The foundation of handling type 2 diabetes is lifestyle changes. The use of pharmacological agents should supplement diet and exercise and should not replace them. Research reveals that intensive lifestyle interventions prevent the progression of impaired glucose tolerance and diabetes effectively than metformin. Nevertheless, African Americans lack intensification of treatment and thus do not achieve adequate glycemic control. The population does not comply with self-monitoring or adhere to treatment due to economic factors, literacy levels, sociocultural factors and lack of diabetes education (Chlebowy et al., 2019). These challenges can be dealt with if providers follow the recommendation from the American Diabetes Association. The presence of genetic data may impact the population health management. In other words, the data may be used in the study of other factors or conditions that may be associated with type 2 diabetes. For instance, data on obesity among African Americans may be applied in the determination of the presence of hemoglobin A1C, a genome linked to the type 2 diabetes.

Potential Solution for Solving the Problem of Type 2 Diabetes

Among African Americans

One of the potential solution to type 2 diabetes is lifestyle change. Embracing physical exercise and eating healthy is essential in reducing health complications that lead to diabetes. Also, there is the need for interventions, facilitating preventive factors and practices that can lower in the incidences if type 2 diabetes among African Americans (Konstantinos, 2018). The adoption or application of the nurse-led diabetes self-assessment education may often lead to the reduction of complications caused by the conditions, as well as other conditions such as end-stage renal diseases. Assessments are important in ensuring earlier diagnosis and as well as the development of appropriate interventions that may enable patients adhere to the control measures aimed at prolonging their lives.

PICOT Statement

African Americans are vulnerable to type 2 diabetes due to their lifestyle and the inability to get quality care from healthcare institutions. When compared to other races, African Americans lead with the highest number of infections of type 2 diabetes.

PICOT Question

What are some of the potential solution to type 2 diabetes among African Americans?

How the Solution Incorporate Health Policies

The solution to type 2 diabetes among African Americans incorporate different health policies and goals that support healthcare quality. The general goals of the healthcare institution is to ensure a healthy population. Encouraging physical exercise and lifestyle change is a general call that ensure reduction in the cardiovascular diseases associated with type 2 diabetes. Health policies also stipulate that prevention is better than cure. Therefore, with the intervention mechanisms from both the healthcare system and personal decisions, it will be much easier to control diabetes among African American population. Increasing the quality of life among the African Americans who have Type 2 diabetes is an essential step that would ensure a reduction in deaths as well as the severity of the disease.

References

Carpenter, R., DiChiacchio, T., & Barker, K. (2019). Interventions for self-management of type 2 diabetes: An integrative review. International journal of nursing sciences, 6(1), 70-91. https://doi.org/10.1016/j.ijnss.2018.12.002

Chlebowy, D. O., Batscha, C., Kubiak, N., & Crawford, T. (2019). Relationships of Depression, Anxiety, and Stress with Adherence to Self-Management Behaviors and Diabetes Measures in African American Adults with Type 2 Diabetes. Journal of racial and ethnic health disparities, 6(1), 71-76. https://doi.org/10.1007/s40615-018-0500-3

Hu, J., Amirehsani, K. A., Wallace, D. C., McCoy, T. P., & Silva, Z. (2016). A family-based, culturally tailored diabetes intervention for Hispanics and their family members. The Diabetes Educator, 42(3), 299-314. https://doi.org/10.1177/0145721716636961

Konstantinos, K. (2018). Self-Care Management of African American Men with Type 2 Diabetes. Walden University, ProQuest Dissertations Publishing. https://scholarworks.waldenu.edu/dissertations/4930/

  < Nephrology Research> < The distinction between structured (practical) and unstructured (theoretical) research in clinical trials > Observations (Similarities/Differences)
Methodology  

The T1, T2 and T3 translational studies compel the researcher to directly participate in the study variables with the sole intention of achieving the research objectives. The research full controls both the independent and dependent variables throughout the life of the study. For each of the three studies, the following methodologies are seen:

T1: Case studies, Phases I & II Clinical Trials, and observational studies.

T2: Phase IV Clinical trials, Diffusion research, Dissemination research and Implementation Research.

T3: Evidence synthesis, Guidelines, Observations, and Phase III Clinical Trials

 

 

 

 

Traditional practices also have their own methodologies. They are different as thus:

Qualitative: Boyack et al. (2014) reveals that qualitative studies have adopt observations, focus groups, observation, and individual depth interviews to obtain data.

Quantitative: These studies utilize methods such as surveys, simulations and audits to get data.

Translational research and traditional research are complex endeavors that lead to the adoption of hypothesis in order to formulate clinical decisions.

Further, the researchers in both studies are required to establish a design and then take part in the research process.

However, translational research undertakings are monitored closely so as to answer certain biomedical issues.

Goals  

T1: Formulating treatments as well as interventions (Harrington & Hauskeller, 2014).

T2: Implementation and Dissemination of research outcomes to effect system-wide change (Ullah, 2017).

T3: Testing efficaciousness and effectiveness of the formulated interventions and treatments (Ortiz, 2015).

 

 

 

 

The qualitative studies are used to formulate a comprehension of the underlying causes as well as motivations (Boyack et al., 2014). They further reveal prevalent trends in opinions and thoughts. On the other hand, quantitative studies seek to identity data and then make a generalization of the results predicated upon a certain sample to the population that a researcher is interested in studying. Translational research addresses a certain health care policy with a view of integrating evidence-based solutions into practice. Nevertheless, traditional research seeks to examine human behavior as well as discover facts concerning a certain phenomenon in the social sphere.
Data Collection The data for the studies were obtained from clinical trials, practice-based research networks as well as population –based interventions.

 

 

 

 

 

The collection of data for qualitative studies occur through participant observation. However, when it comes to quantitative research, the same process is achieved through measuring of variables. Whereas translational research entails the implementation of research study outcomes in practice, traditional studies principally entail analyzing obtained data using multifarious statistical tools.

 

 

 

References

Boyack, K. W., Patek, M., Ungar, L. H., Yoon, P., & Klavans, R. (2014). Classification of individual articles from all of science by research level. Journal of Informetrics8(1), 1-12.

Harrington, J., & Hauskeller, C. (2014). Translational research: an imperative shaping the spaces in biomedicine. TECNOSCIENZA: Italian Journal of Science & Technology Studies5(1), 191-202.

Ortiz, A. (2015). Translational nephrology: what translational research is and a bird’s-eye view on translational research in nephrology. Clinical kidney journal8(1), 14-22.

Ullah, M. H. (2017). TRANSLATIONAL RESEARCH. Advances in Basic Medical Sciences (PMDC Recognized)1(1).

Translational Research Graphic Organizer

Use the “Translational Research Graphic Organizer Template” to compare three types of translational research with traditional (qualitative or quantitative) research. Make sure to include methodology, goals, and data collection in your organizer.

You are required to cite three to five sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

You are not required to submit this assignment to LopesWrite.

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Assignment: NUR 550 Translational Research
Assignment: NUR 550 Translational Research

What is Translational in health?

THE TRANSLATION OF THE ACHIEVEMENTS FROM BASIC SCIENCE into everyday clinical practice remains an important issue in contemporary health, and is addressed through the new subject of translational research, which aims to bridge the gap between basic research and its application in health. At first, it connected bench (basic) to bed research (clinical applications), which is also known as benchside-to-bedside research2. The definition of translational research has evolved over time, ceasing to be a field linked to clinical research, with perspectives that were mainly focused on the development of new health technologies.

Re: Topic 1 DQ 1

Translational research is form of clinical research that was first seen around 1993 (Rubio et al, 2010). So as far as research goes this is a fairly new was to look into things. There is also no clear definition of translational research, but essentially it encompasses two areas of translation one being the information obtained in pre-clinical studies, lab research and the other being the adaptation of best practices in the community with their cost effectiveness (Rubio et al, 2010). There are three levels of translational research, starting with T1, which involves the beginning research or development of an intervention, including the lab research, observational research and phase I and II clinical trials (Translational Research, n.d.). The second level is T2 the translation to patients, testing these interventions and their efficacy on the patient populace, including phase III clinical trials, studying how these new interventions work with disease processes and creating new guidelines with up-to-date information (Translational Research, n.d.). The third level is T3 disseminating and implementation of all the research into daily practice, creating the research evidence found into evidence-based practices across the profession (Translational Research, n.d.).

From this information there isn’t a difference between evidence-based practice and translational research, it is just a way to get to evidence based practice. By following the ‘three T’s’, the final step is to put all of this research into practice, as evidence-based practice. For public health this means the most up to date care and information as the natural progression of translational practice ends with practice. If there is no research being done in the area however, this has a negative impact on the population, as there is not up to date EPB related to that disease process and/or its co morbidities.

Rubio, D. M., Schoenbaum, E. E., Lee, L. S., Schteingart, D. E., Marantz, P. R., Anderson, K. E., Platt, L. D., Baez, A., & Esposito, K. (2010). Defining translational research: implications for training. Academic medicine : journal of the Association of American Medical Colleges85(3), 470–475. https://doi.org/10.1097/ACM.0b013e3181ccd618

Translational Research – Defining the “T’s” | Translational Cancer Research Network. (n.d.). Www.Tcrn.Unsw.Edu. Retrieved June 18, 2021, from http://www.tcrn.unsw.edu.au/translational-research-definitions

 

RESPOND HERE (150 W0ORDS, 2 REFERENCES)

 

This is insightful Sarah, translational research is form of clinical research that was first seen around 1993. So as far as research goes this is a fairly new was to look into things. Translational research refers to a form of study that seeks to produce more applicable, meaningful and valid outcomes that can directly impact human health. The main objective or purpose of the translational research is to translate essential science discoveries more quickly and efficiently into practices (Eske, 2020). Translational research has been applied frequently by different researchers to enhance research processes geared towards achieving quality treatment processes and effective patient outcomes. There are three major level of translational research including T1, T2, and T3. These levels need to be incorporated into the research processes to ensure accuracy and effective outcomes in the research processes (Woolf, 2018). Level I or T1 often involves development of interventions to ensure that the entire research processes is done effectively in line with the set objectives.

References

Woolf, S. H. (2018). The meaning of translational research and why it matters. Jama299(2), 211-213. https://jamanetwork.com/journals/jama/article-abstract/1149350