NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

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While searching for an appealing translational research paper in the GCU library, I came across “Enhanced differentiation of human dopaminergic brain cell model for preclinical translational research in Parkinson’s disease.” Harischandra and her colleagues in 2020 While there are treatments for Parkinson’s disease, such as deep brain stimulation and drugs like levodopa, this study discovered that these only scratch the surface of the problem (Harischandra et. al, 2020). They claim that dopaminergic neurons and dopamine transporters must be studied in order to better treat these people in the future (Harischandra, et. Al, 2020). When they tried to conduct experiments on rats, they discovered that the cells diverged in such a way that they could not obtain reliable results (Harishchandra, et. Al, 2020). The researchers then generated LUHMES cells from embryonic stem cells that were more closely linked to the pathways they hoped to establish (Harischandra, et. Al, 2020). They are in the T1 phase because they are studying these cells, which includes patient preparation and practice, as well as laboratory research on the actual effects on brain circuits (Translational Research, n.d.). I won’t lie: the study was extensive, and the method they used required a lot of chemicals and days of watching these cells grow into what they needed, but their processes significantly increased the cells’ ability to reabsorb dopamine after five days (Hasichandra, et. Al, 2020). Because stem cells are not always available for drug development, the ability to generate these LUHMES cells for testing is extremely beneficial for future Parkinson’s research and medication testing (Harischandra et. Al, 2020).

PICOT Draft

Part 1: Propose a relevant nursing practice problem for an evidence-based practice project. Explain why you selected this topic and how it is relevant to advance nursing practice. Include one research article that demonstrates support for the nursing practice problem.

Nurses must work without being overburdened in order to provide optimal health care to all populations. However, in the last decade, the number of patients visiting health care facilities due to obesity and related complications has skyrocketed. Children and adolescents in school are among the most vulnerable demographics. Childhood obesity is my nursing practice problem for an evidence-based practice project. According to Robinson et al. (2017), sedentary activities such as playing video games or watching television for extended periods of time have increased children’s susceptibility to obesity. I chose this topic because of the rising mortality and morbidity rates associated with childhood obesity. Obese school-age children are more likely to develop chronic diseases like heart disease and diabetes, which can impair their quality of life (Che et al., 2018; De Lorenzo et al., 2019). These health outcomes increase the burden of illness on health care organizations, families, society, and the workloads of nurses. Nurses should conduct research on health-care issues that directly affect their profession and respond with evidence-based solutions. Stiglic and Viner (2019) cited a relevant paper that directly supported the issue of poor nursing practice. Obesity has undeniably negative consequences for children’s health, and treatments such as screen time restriction can help. Nurses can help patients and families understand obesity concerns, educate them on recommended screen time for children, and encourage parents to limit their children’s screen time. This will aid in the improvement of health outcomes.

Read Also: NUR 550 Week 2 Discussion question

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Part II: In the table below, describe the population and the intervention. (You will continue drafting the PICOT, completing the shaded areas in Topic 3.)
PICOT Question
P Population School-age children with obesity
In the United States, childhood obesity has reached epidemic proportions. Because obesity impacts the physical, psychological, and cardiovascular health of the afflicted people, it is a significant public health issue. Obesity rates among youth ages 6 to 19 in the United States have tripled since the 1970s, according to data from 2015-2016. (Centers for Disease Control and Prevention, 2018). Poor eating habits, a lack of physical activity, a family history of the disease, and traumatic experiences in childhood are all potential risk factors. Consequently, urgent, evidence-based, and population-driven initiatives are needed to stem the tide of rising rates.
I’m the one doing the intervening Reduced screen time

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment


School-age students are becoming more sedentary as a result of their increased screen use. It has been found that watching television or other screen media promotes obesity risk factors such as binge eating, sleep deprivation, and the consumption of high-sugar, low-nutrient foods. More screen time also exposes youngsters to marketing that effects their food preferences and eating habits. As a result, limiting children’s exposure to screen time is an excellent intervention for lowering obesity among children and adolescents..

ALSO CHECK OUT: NUR 550 Topic 2 DQ 1 Explain the value of biostatistics in population health research

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

Learners will select a valid nursing practice problem for an evidence-based practice project proposal. The project will be completed in sections, beginning in NUR-550 and culminating in a final written paper detailing the evidence-based practice proposal in NUR-590.

The purpose of this assignment is to select a relevant nursing practice problem for your evidence-based practice project proposal. To identify a relevant problem, consider problems generally faced in nursing practice (coordination of health care, assessment, education, patient support, trauma prevention, recovery, health screenings, etc.).  Use the “PICOT Draft” template to complete this assignment.

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment
NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

Use a national, state or local population health care database to research indicators of disparity. Choose a mortality/morbidity indicator to identify a clinical problem or issue that you want to explore pertaining to a population of focus. Use this indicator to begin to formulate a PICOT statement.

Refer to the “Evidence-Based Practice Project Proposal – Assignment Overview” document for an overview of the evidence-based practice project proposal assignments.

You are required to cite one peer-reviewed source to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.

While APA style is not required for the body of this assignment, solid academic writing is expected, and documentation of sources should be presented using APA formatting guidelines, which can be found in the APA Style Guide, located in the Student Success Center.

NUR 550 Evidence-Based Practice Project Proposal Identification of Nursing Practice Problem Assignment

This assignment uses a rubric. Please review the rubric prior to beginning the assignment to become familiar with the expectations for successful completion.

Re: Topic 1 DQ 1

Translational research is form of clinical research that was first seen around 1993 (Rubio et al, 2010). So as far as research goes this is a fairly new was to look into things. There is also no clear definition of translational research, but essentially it encompasses two areas of translation one being the information obtained in pre-clinical studies, lab research and the other being the adaptation of best practices in the community with their cost effectiveness (Rubio et al, 2010). There are three levels of translational research, starting with T1, which involves the beginning research or development of an intervention, including the lab research, observational research and phase I and II clinical trials (Translational Research, n.d.). The second level is T2 the translation to patients, testing these interventions and their efficacy on the patient populace, including phase III clinical trials, studying how these new interventions work with disease processes and creating new guidelines with up-to-date information (Translational Research, n.d.). The third level is T3 disseminating and implementation of all the research into daily practice, creating the research evidence found into evidence-based practices across the profession (Translational Research, n.d.).

From this information there isn’t a difference between evidence-based practice and translational research, it is just a way to get to evidence based practice. By following the ‘three T’s’, the final step is to put all of this research into practice, as evidence-based practice. For public health this means the most up to date care and information as the natural progression of translational practice ends with practice. If there is no research being done in the area however, this has a negative impact on the population, as there is not up to date EPB related to that disease process and/or its co morbidities.

Rubio, D. M., Schoenbaum, E. E., Lee, L. S., Schteingart, D. E., Marantz, P. R., Anderson, K. E., Platt, L. D., Baez, A., & Esposito, K. (2010). Defining translational research: implications for training. Academic medicine : journal of the Association of American Medical Colleges85(3), 470–475. https://doi.org/10.1097/ACM.0b013e3181ccd618

Translational Research – Defining the “T’s” | Translational Cancer Research Network. (n.d.). Www.Tcrn.Unsw.Edu. Retrieved June 18, 2021, from http://www.tcrn.unsw.edu.au/translational-research-definitions

 

RESPOND HERE (150 W0ORDS, 2 REFERENCES)

 

This is insightful Sarah, translational research is form of clinical research that was first seen around 1993. So as far as research goes this is a fairly new was to look into things. Translational research refers to a form of study that seeks to produce more applicable, meaningful and valid outcomes that can directly impact human health. The main objective or purpose of the translational research is to translate essential science discoveries more quickly and efficiently into practices (Eske, 2020). Translational research has been applied frequently by different researchers to enhance research processes geared towards achieving quality treatment processes and effective patient outcomes. There are three major level of translational research including T1, T2, and T3. These levels need to be incorporated into the research processes to ensure accuracy and effective outcomes in the research processes (Woolf, 2018). Level I or T1 often involves development of interventions to ensure that the entire research processes is done effectively in line with the set objectives.

References

Woolf, S. H. (2018). The meaning of translational research and why it matters. Jama299(2), 211-213. https://jamanetwork.com/journals/jama/article-abstract/1149350

Eske, J. (2020, August 31). In vivo vs. in vitro: What is the difference? Medical News Today. Retrieved June 17, 2021, from https://www.medicalnewstoday.com/articles/in-vivo-vs-in-vitro

Re: Topic 1 DQ 1

Translational research is a new concept in my view of the world, it is a fairly new concept, as nurses we hear the term evidence-based practice (EBP) and research. Translational research is often thought of as EPB, Translational research is the research of EBP studies as well as the study and translation of EBP interventions into practice (Melnyk & Fineout-Overholt, 2019) Translational research is as stated it translates how EBP “translates” into practice, evidence-based practice is a guide to practice, translation science is the translation to implement the evidence-based research into practice. (Tilter, 2018). Translation research has different components to implementation of preclinical studies, phase one small clinical trials, phase 2&3 larger clinical trials, outcomes from the clinical trials, them phase 5 population outcomes research- these phases offer a “bench to bedside” continuum (Tilter, 2018).

Gaps between the availability of evidence and the placing evidence into practice has shown to partner with poor outcomes by not enabling caregivers to place the evidence into practice. (Tilter, 2018)Transitional research has shown to be beneficial in-patient outcomes and health care management by translating the evidence into practice which improves patient outcomes by the utilization of the evidence. In my field of Labor and delivery I have seen this similar process in the abundance availability of research and evidence of the increased risk of hypertension in pregnancy. Yet the physicians I practice with implement in very many ways through lack of translation causing early inductions and higher risk to the infants. When implementing a new technology, evidence or practice it is important to understand the research and evidence behind it as well as how best to safely implement into practice. (Sung et al., 2020) Translation research is an exciting and has multiple opportunities to advance patient outcomes, as an upcoming APRN in a magnet hospital, utilizing this process with EBP will strongly improve patient care as well as nursing practice.

 

References

Melnyk, B. M., PhD, RN. APRN-CNP, FAANP, FNAP, FAAN, & Fineout-Overholt, E., PhD, RN, FNAP, FAAN. (2019). Evidence-Based Practice in Nursing& Healthcare A Guide to Best Practice (4th ed.). Wolters Kluwer.

Sung, V. W., MD MPH, Tulikangas, P., MD, Bradley, C. S., MD, MSCE, & Rideway, B., MD. (2020). Assessing and adopting New medical devices for Obstetric and Gynecologic care. ACOG135(4), 160–166. Retrieved May 26, 2021, from

Tilter, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues in Nursing23(2). Retrieved June 16, 2021, from

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NUR-550 Course Objectives

Description:

In this course, the student will:

1. Explore research articles, nursing and related theories, applying levels of evidence, and theoretical frameworks to identify quality research studies.
2. Demonstrate understanding of scientific inquiry, knowledge generation, utilization, and dissemination in advanced nursing practice.
3. Evaluate the evidence for potential solutions/innovations that can potentially solve a health care issue and improve patient outcomes.
4. Identify gaps in nursing knowledge and evidence-based practice that can potentially be resolved by planning and implementing a practice change project.
5. Formulate a clinically researchable question amenable to an innovative evidence-based practice change proposal.
6. Write a scholarly literature review that supports a clinically researchable question amenable to an innovative evidence-based practice change proposal.
7. Evaluate health policy and advocacy issues for the purpose of improving health care outcomes.
8. Engage in scientific inquiry into the state of health care delivery, patient-centered care, and ethical principles related to health beliefs, health promotion, and risk reduction of diverse populations.
9. Propose quality improvement initiatives that advance the delivery of safe, high-quality health care.
10. Use principles from epidemiology, biostatistics, genetics, genomics, and cultural competence to guide comparisons of various patient populations.

The selected nursing issue for the evidence-based practice (EBP) project is medication errors in nursing that happen due to staffing shortage. Medication errors are a significant problem in healthcare sector, especially at this time when there is nursing shaortage and high nurse turnovers. With reduced number of nurses working in the healthcare sector, the susceptibility of patients to medication errors increases, particularly adverse drug events that can lead to death and prolonged stays in hospitals (Buerhaus et al., 2017). The project will focus on the effectiveness of implementation of health information technology compared to the conventional ways of medication management to mitigate medication errors in critically ill patients. The selection of critically ill patients as the population of interest emanates from their increased vulnerability to injuries that need high-risk medication and more use of intravenous infusions which rises the possibility of medication errors. Health information technology can play an essential role in enhancing efficiency of nurses to offer required care and reduce medication errors.

While errors are inevitable and lead to detrimental effects on patients, healthcare providers can leverage technological tools to reduce their likelihood through establishing appropriate measures. Health systems and providers can reduce the problem through organization-wide processes and not just through medication administration component alone (Trimble et al., 2017). Due to the increased demand on healthcare services that has resulted in provider shortage, health information technology can offer solutions to the issue. The EBP project will delve into the issue using evidence-based practice intervention and translational research to provide possible solutions to the health systems and practitioners like nurses.

5 percent sources required There are no references provided. Only a subset of the necessary sources have been obtained. Although sources are gathered, some are out of date or ineffective. The necessary number of sources has been obtained. Despite their reputation as reliable sources, not all sources are appropriate for the assignment criteria and nursing topic. The necessary resources have been obtained. They are current and relevant to the assignment’s requirements as well as nursing topics. NUR 550 Evidence-Based Practice Project Proposal Assignment: Identifying a Nursing Practice Problem

Mechanics Writing Instructions (includes spelling, punctuation, grammar, and language use) 5 percent of the overall There are so many surface flaws that they obstruct meaning transmission. Words and sentences are being used incorrectly. Mechanical flaws that occur frequently and repeatedly distract the reader. Inconsistencies in the language used (the register) or the words used can be detected. The sentence pattern is lacking in variety. There are a few mechanical issues or typos, but they aren’t particularly bothersome to the readers. The audience-friendly language and sentence structure are used. Although there may be some mechanical errors, the prose is generally error-free. The author employs effective sentence structures and figures of speech. Writing in normal, written academic English is obvious. NUR 550 Evidence-Based Practice Project Proposal Assignment: Identifying a Nursing Practice Problem

Keeping track of the sources that were used (citations, footnotes, references, bibliography, etc., as appropriate to assignment and style) 5 percent of the overall The sources have received insufficient documentation. Inconsistent or incorrect source documentation, as relevant to the assignment and style, with multiple formatting issues Source documentation is completed in accordance with the assignment and style guidelines, but minor formatting issues may occur. The sources are cited correctly, and the formatting is generally correct. “It is obvious that you are writing in proper, written, academic English.
The format is flawless, and all sources are properly cited and referenced.”

Re: Topic 1 DQ 1

EBP is the process of combining evidence from studies, clinical expertise, and patient values and preferences to reach a decision that promotes the best patient-centered care (Nurse.com, 2021). However, it has been noted that much evidence-based practice takes time to implement and frequently does not progress beyond publication in a professional journal (Weiss et al., 2018). According to Titler (2018), there is a disconnect between EBP recommendations and their actual implementation to help improve patient care. Translational research is used as a result of this. Translational research is the process of incorporating evidence-based interventions into real-world clinical settings (Melnyk & Fineout-Overholt, 2019). Translational science encompasses the process of translational research, which includes EBP.

Although both EBP and translational research are related, they are not to be used interchangeably (Titler, 2018). According to Titler (2018), EBP is the application of evidence while translational research is the implementation of the evidence into practice. This includes executing knowledge, research designs and methods into real-life in practice, communities and public health settings. Translational research focuses on applying these EBP interventions to help improve patient outcomes, and to determine what strategies work for whom, why they work, and in what environment they work in (Titler, 2018).

There are five phases of translational research, which are known as “bedside to community” (Titler, 2018). The first phase, T0, refers to basic science research which includes preclinical and animal studies. After this, a phase 1 clinical trial must be done, to test the safety in a small group of humans, which is known as the T1 phase. The next phase of translational research, T3, includes both phase 2 and 3 clinical trials which tests the safety in a larger group of people and allows for comparison of common treatments. Phase four, or T4, includes phase 4 clinical trials and outcomes research which can be applied into practice. Lastly, phase five (T5) consists of a translation to the community, in which the larger population outcomes research is obtained (Titler, 2018). Translational research can be seen with the implementation of vaccinations. After evidence and research is conducted in regard to the particular disease and vaccine components, the application of the scientific evidence can be applied in trials to see how the product of the research can be used effectively in practice (Centers for Disease Control and Prevention, 2020).

References

Centers for Disease Control and Prevention. (2020, December 17). Topic area 5: Translational

          research. https://www.cdc.gov/niosh/programs/review/ecb/topic5.html

Melnyk, B. M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing &

          healthcare: A guide to best practice. Wolters Kluwer.

Nurse.com. (2021). Evidence-based practice. https://www.nurse.com/evidence-based-practice

Titler, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues

in Nursing, 23(2), 1. https://doi-org.lopes.idm.oclc.org/10.3912/OJIN.Vol23No02Man01

Weiss, M. E., Bobay, K. L., Johantgen, M., & Shirey, M. R. (2018). Aligning Evidence-Based

Practice With Translational Research: Opportunities for Clinical Practice Research.

JONA: The Journal of Nursing Administration, 48(9), 425–431.

https://doi-org.lopes.idm.oclc.org/10.1097/NNA.0000000000000644

https://doi-org.lopes.idm.oclc.org/10.1097/NNA.0000000000000644

https://doi-org.lopes.idm.oclc.org/10.1097/NNA.0000000000000644

The type of translational research conducted in this study was T1. T1 translational research involves the development of treatments and interventions (Vukotich, 2016). In this study, a multidisciplinary approach was employed to improve nutrition in preterm neonates. Although approved nutritional guidelines were in place, routine chart audits revealed noncompliance (Page et al., 2017). Therefore, an evidence–practice gap existed. The researchers’ goal was to identify barriers to the timely delivery of the appropriate nutrition in a tertiary‐level Neonatal Critical Care Unit through the development of an implementation project to ensure best practices (Page et al., 2017). Information was obtained via individual interviews with medical and nursing staff and digitally recorded with informed consent of the participants (Page et al., 2017). After analysis of the interview questions, the data highlighted inconsistent practice and a lack of adherence to guidelines regarding nutritional support as a barrier to achieving optimal early nutrition (Page et al., 2017). As a result of this study, appropriate and specific interventions were developed, implemented, and evaluated (Page et al., 2017).

T1 translational research was conducted because interventions were needed to increase compliance with following nutritional guidelines in the treatment of preterm neonates. New knowledge was gained to enhance patient care and improve patient outcomes. Furthermore, the interventions developed were intended to change behaviors and bridge the evidence–practice gap.

References

Page, D., Gilroy, M., Hurrion, E., Clark, L., & Wilkinson, S. (2017). Optimising early neonatal nutrition using translational research methodology. Nutrition & Dietetics74(5), 460–470. https://doi-org.lopes.idm.oclc.org/10.1111/1747-0080.12333

Vukotich, C. J., Jr. (2016). Challenges of T3 and T4 translational research. Journal of Research Practice12(2). Retrieved from http://jrp.icaap.org/index.php/jrp/article/view/552/454

Topic 1 DQ 2

Using the GCU Library (notably the GCU Library: Nursing and Health Sciences Research Guide), find a database, journal, or other collection of resources that focuses on translational research. Select a population health problem or issue of interest from the available studies. What type of translational research is used for the study? Provide rationale as to why this is the best.

Re: Topic 1 DQ 2

For the first time in history, stroke incidence has decreased in the United States in recent years. However, the incidence of stroke in older adults has always been higher than in younger adults, particularly in older women (Portz et al., 2018). Older adults aged 80 and up account for approximately 17% of all stroke patients and are at a high risk of mortality and prolonged hospital stays (Portz et al., 2018). This journal is in the T4 stage of translational research, where the previous stages’ findings are disseminated and implemented. The goal of this translational study was to look into the effects of physical fitness and exercise on older adults with chronic stroke. A substantial body of literature has investigated the relationship between self-management interventions such as physical fitness.

Based on the previous literature, Portz et al. (2018) used the information to investigate whether physical fitness and exercise would be used as a clinical intervention for managing chronic stroke. After implementing the information, Portz et al. (2018) found that it is essential for health care professionals to incorporate self-management interventions such as physical fitness and exercise in managing chronic stroke among older adults. This will improve their quality of life, strength, and endurance by incorporating yoga practice. Furthermore, this kind of research will encourage more health care researchers to conduct translational research to reach phase 4 (T4), where yoga practice can be used as an evidence-based intervention for chronic stroke.

References

Portz, J. D., Waddington, E., Atler, K. E., Van Puymbroeck, M., & Schmid, A. A. (2018). Self-management and yoga for older adults with chronic stroke: A mixed-methods study of physical fitness and physical activity. Clinical Gerontologist, 41(4), 374–381. https://doi-org.lopes.idm.oclc.org/10.1080/07317115.2016.1252453

Schmid, A. A., Miller, K. K., Van Puymbroeck, M., & DeBaun-Sprague, E. (2014). Yoga leads to multiple physical improvements after stroke, a pilot study. Complementary Therapies in Medicine, 22(6), 994–1000. https://doiorg.lopes.idm.oclc.org10.1016/j.ctim.2014.09.005

Topic 1 DQ 1

Identify the different levels of translational research. Explain how translational research is different from evidence-based practice and discuss application to population health management.

Re: Topic 1 DQ 1
Melnyk and Fineout-Overholt (2019) state translational research is often confused with evidence-based practice (EBP). The EBP process involves a critical appraisal of multiple bodies of evidence to make recommendations about patient care. EBP takes clinician expertise and combines it with multiple studies, patient/family preferences and values, to enhance health care quality, improve patient outcomes, reduce costs, and empower clinicians. Translational research, in comparison, studies how EBP interventions translate into real-world clinical settings. Also known as implementation science, translation science focuses on testing implementation interventions to improve the use of evidence to improve patient outcomes and population health (Titler, 2018). It also clarifies what implementation strategies work for whom, in what settings, and why. EBP is the actual application of evidence into practice, or the “doing of” where translational science is research steps to take discoveries “from the bench to the bedside and back again” (Fort et al., 2017).Although the concept of translational research has been widely used and applied in the scientific literature for more than a decade, and there is little agreement between definitions, five phases (T0-T4) remain as an emerging consensus (Fort et al., 2017).5 Phases of Translational Research

  • T1 involves processes that bring ideas from basic research through early testing in humans.
  • T2 involves the establishment of the effectiveness of an intervention in humans and particularly the establishment of clinical guidelines
  • T3 primarily focuses on the implementation and dissemination of research
  • T4 focuses on outcomes and effectiveness in populations
  • T0 phase is relatively rare but involves steps to close the research cycle, wrapping back around to basic research to T1

One reason governments fund research is for the value it provides to society at large (Luke et al., 2017). Benefits to translational research cover four domains: clinical and medical, community and public health, economic benefits, and policy/legislative.

Community and Public Health Specific Benefits

  • Health Promotion
    • Disease prevention/reduction
    • Life expectancy/quality of life
  • Characteristics of Health Care
    • Accessibility
    • Delivery
    • Quality
  • Health Activities and Products
    • Education resources
    • Community health services

Resources

Fort, D. G., Herr, T. M., Shaw, P. L., Gutzman, K. E., & Starren, J. B. (2017). Mapping the evolving definitions of translational research. Journal of Clinical and Translational Science1(1), 60–66. https://doi.org/10.1017/cts.2016.10

Luke, D. A., Sarli, C. C., Suiter, A. M., Carothers, B. J., Combs, T. B., Allen, J. L., Beers, C. E., & Evanoff, B. A. (2017). The translational science benefits model: A new framework for assessing the health and societal benefits of clinical and translational sciences. Clinical and Translational Science11(1), 77–84. https://doi.org/10.1111/cts.12495

Melnyk, B. M., & Fineout-Overholt, E. (2019). Evidence-based practice in nursing & healthcare: a guide to best practice. Wolters Kluwer.

Titler, M. G. (2018). Translation Research in Practice: An Introduction. Online Journal of Issues in Nursing23(2), 1. https://doi.org/10.3912/OJIN.Vol23No02Man01

Topic 1 DQ 2

Using the GCU Library (notably the GCU Library: Nursing and Health Sciences Research Guide), find a database, journal, or other collection of resources that focuses on translational research. Select a population health problem or issue of interest from the available studies. What type of translational research is used for the study? Provide rationale as to why this is the best.

Topic 1 DQ 1

The burden of cervical cancer is increasingly gaining prominence among the population and it the fourth leading cause of cancer-related deaths among women internationally. Particularly, women aged between 20 and 35 are highly impacted (Kong et al., 2019). Therefore, the proposed change initiative is the provision of evidence-based education on cervical cancer screening. Cancers are grouped into various stages based on the level of progress and metastasis. Individuals in initial stages of cancer have high probability of survival. As such, provision of education on cervical cancer screening among women aged between 20 and 30 years is critical in early detection and management of cervical cancer. The screening services are widely available at affordable prices. However, lack of knowledge on the essence and misconceptions in the society have discouraged many women from screening. Therefore, the role of education program is to create awareness of the essence of cervical screening. Education is also critical in addressing the misconceptions in the society that may discourage the target population from going for screening. Moreover, the education will provide relevant information on cervical cancer prevention.

The setting for this program is health care facility where different women come to seek medical attention. The mobilization will be done by community health workers, religious organizations, and various community leaders to ensure more participants for the project. As a nurse, my responsibility in the success of the project include coordinating education program, carrying out follow-up, ensure continuity in the entire process, ensure provision of updated and relevant information to enhance patient knowledge and choice, coordinate different levels of care, and lead research and publication processes. Finally, this project generated qualitative and quantitative research outcomes that facilitate differentiation of positive outcomes with this education program intervention. If the outcome of this project proves that evidence-based education on cervical cancer screening can foster early detection of cervical cancer, the PICOT can be amenable to research.

 

References

Kong, Y., Zong, L., Yang, J., Wu, M., & Xiang, Y. (2019). Cervical cancer in women aged 25 years or younger: A retrospective study. Cancer Management and Research11, 2051-2058. https://doi.org/10.2147/cmar.s195098

 

Re: Topic 1 DQ 2
According to the Centers for Disease Control (CDC), 34.2 million people in the United States have diabetes with 7.3 million people being undiagnosed with the highest percentage of 5.4 % being in individuals greater than or equal to 65 years of age (CDC, 2020). Of those that are undiagnosed, the highest percent of 4.6% is in the Asian and non-Hispanic population (CDC, 2020). When looking through the database I came across an article on Niclosamide ethanolamine salt (NEN) improving diabetes and diabetic kidney disease in mice. Diabetes is a problem worldwide and definitely leads to renal complications along with other challenges (Han et al., 2018). This study looked at the use of NEN and how it could improve diabetic symptoms in type 1 diabetes (T1D) as evidence has shown that it could improve diabetic symptoms in individuals with type 2 diabetes (T2D).In this study the use NEN was shown to increase serum insulin levels and slow the progression of diabetic kidney disease in T1D (Han et al., 2018). What I found interesting in this article was that the control mice showed high fasting blood glucose levels, hemoglobin A1c levels, and urine glucose levels and when treating other T1D mice with NEN for 8 weeks, the results showed that NEN significantly reduced the blood glucose levels in these mice (Han et al., 2018). This study could be promising for future treatment with T1D patients and slowing the progression of diabetic kidney disease. The testing in this study was performed on mice making this a T0 translational research study. This level/phase of translational research is best for this study so that no human subjects are harmed in the preclinical studies until the safety of the intervention has been determined.References:Centers for Disease Control and Prevention (CDC). (2020). Prevalence of both diagnosed and undiagnosed diabetes. https://www.cdc.gov/diabetes/data/statistics-report/diagnosed-undiagnosed-diabetes.htmlHan, P., Shao, M., Guo, L., Wang, W., Song, G., Yu, X., Zhang, C., Ge, N., Yi, T., Li, S., Du, H., & Sun, H. (2018). Niclosamide ethanolamine improves diabetes and diabetic kidney disease in mice. American Journal of Translational Research, 10(4), 1071-1084.